Purpose/Usage

Propecia is indicated for the treatment of men with male pattern hair loss (androgenetic alopecia) to increase hair growth and prevent further hair loss. Propecia is not indicated for use in women or children. Propecia is not effective in postmenopausal women with androgenetic alopecia. Propecia is a new, effective treatment to help prevent further hair loss in men. Unlike previous treatments it is available in a convenient tablet form that is taken once daily.

Male pattern hair loss is a common condition in which men experience thinning of the hair on the scalp. Often this results in a receding hairline and/or balding on the top of the head. These changes typically begin gradually in men in their 20s.

Doctors refer to this type of hair loss as androgenetic alopecia. Researchers in this area believe male pattern hair loss is due to heredity and is dependent on a hormone called dihydrotestosterone (DHT). DHT contributes to a shortening of the growth phase and a thinning of the hair. Men with male pattern baldness have increased levels of DHT in their scalps.

Propecia lowers the levels of a hormone called dihydrotestosterone (DHT) in the scalp and serum by blocking 5 alpha-reductase, an important enzyme involved in regulating the hair follicle. Results of clinical studies: For 12 months, doctors studied over 1800 men aged 18 to 41 with mild to moderate amounts of ongoing hair loss. All men, whether receiving propecia or placebo (a tablet containing no medication) were given a medicated shampoo. Of these men, approximately 1200 with hair loss at the top of the head were studied for an additional 12 months.

In general, men who took propecia maintained or increased the number of visible scalp hairs and noticed improvement in their hair in the first year, with the effect maintained in the second year. Hair counts in men who did not take PROPECIA continued to decrease. This study is now in its fourth year and results will be updated in the near future. 86% of men treated with propecia had no further hair loss, compared to 42% in the placebo treated group (based on any decrease in vertex hair count from baseline at month 12). 48% of men had improved hair growth compared with 7% of men receiving placebo. These results were based on detailed hair counts, photographic assessment by an expert panel of dermatologists, investigator assessment and patient self-assessment questionnaires. In one study, patients were questioned on the growth of body hair. Propecia did not appear to affect hair in places other than the scalp.

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